PhD (Dr.) Tando Maduna

Building vascular networks and Blood-Brain-Barriers

Institute for Anatomy and Cell Biology

Department of Neuroanatomy

Albertstraße 17
D - 79104 Freiburg
Germany

+49 761 203 5109

 tando.maduna@anat.uni-freiburg.de

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Vita

since 2023Postdoctoral Researcher, Department of Neuroanatomy, Institute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, Freiburg
2021 - 2022Postdoctoral Researcher, Biomedical Research Center of Strasbourg, French National Institute of Health and Medical Research (INSERM), Strasbourg University, France
2019 - 2021Postdoctoral Fellow, Neuro Research Group, Department of Physiological Sciences, Stellenbosch University, South Africa
2018Postdoctoral Researcher, Institute of Genetics and Molecular and Cellular Biology (IGBMC), Strasbourg University, France
2017Research Associate, Institute of Cellular and Integrative Neuroscience, CNRS, Strasbourg University
2013 - 2017PhD candidate (sp. Neuroscience), Institute of Cellular and Integrative Neuroscience, CNRS, University of Strasbourg, France
Thesis: “Vasoactive intestinal peptide (VIP) controls the development of the nervous system and its functions through VPAC1 receptor signaling: lessons from microcephaly and hyperalgesia in VIP-deficient mice”
2010 - 2012MSc. student (sp. Neuroscience), Joint Master in Neuroscience, University of Strasbourg, France (magna cum laude)
2009BScMedScHons student (sp. Medical Physiology), Stellenbosch University, South Africa
2005 – 2008BSc student ( sp. Life Science) student, Stellenbosch University, South Africa

Awards

2021Oral Presentation Award, 7èmes Journées De La Recherche SLA/MNM 2021, Annual meeting of the Filière de santé Maladies Rares SLA et Maladies du Neurone Moteur, France
2020Postdoctoral Fellow Award for Exceptional Achievement, Vice-Rector for Research, Innovation And Postgraduate Studies Award, Stellenbosch University, South Africa
2019South African National Research Foundation Knowledge Field Development Grant, Training and Conference Organisation Grant, National Research Foundation and Stellenbosch University, South Africa
2019 - 2021Claude Leon Foundation Postdoctoral Fellowship, The Claude Leon Foundation, South Africa
2013 - 2016South African National Research Foundation Freestanding Doctoral Scholarship for International Study, National Research Foundation, South Africa
2011 - 2012Bourses de l’Ambassade de France MSc Merit Award, France
2010 - 2011Oppenheimer Memorial Trust Fund Grant, MSc Merit Award, Oppenheimer Memorial Trust, South Africa

Other Qualifications

since 2020Reviewer for the Stellenbosch University Social Behavioural and Educational Research Ethics Committee
2020Guest Reviewer for the Journal of Neuroscience Research
2019Member of Stellenbosch University Research Committee
2014Licensed for Animal Handling (according to FELASA-Cat. B)
2014 - 2017Scientific and Administrative Coordinator, Joint Master in Neuroscience Program, Strasbourg University

Selected Publications

  • Reiss D*, Maduna T*, Maurin H, Audouard E and Gaveriaux-Ruff C (2020). Mu opioid receptor in microglia contributes to morphine analgesic tolerance, hyperalgesia, and withdrawal in mice. Journal of Neuroscience Research, 100:203-219. doi: 10.1002/jnr.24626
  • Gabel F, Aubry A-S, Hovhannisyan V, Chavant V, Weinsanto I, Maduna T, Darbon P and Goumon Y (2020). Unveiling the Impact of Morphine on Tamoxifen Metabolism in Mice in vivo. Frontiers in Oncology, 10:25. doi: 10.3389/fonc.2020.00025
  • Maduna T*, Audouard E*, Dembélé D, Mouzaoui N, Reiss D, Massotte D, Gaveriaux-Ruff C (2019). Microglia express mu opioid receptor: insights from transcriptomics and fluorescent reporter mice. Frontiers in Psychiatry, 9:726. doi: 10.3389/fpsyt.2018.00726
  • Weinsanto I, Mouheiche J, Laux-Biehlmann A, Aouad M, Maduna T, Petit-Demoulière N, Chavant V, Poisbeau P, Darbon P, Charlet A, Giersch A, Parat M-O, Goumon Y. Stable isotope‐labelled morphine to study in vivo central and peripheral morphine glucuronidation and brain transport in tolerant mice (2018). British Journal of Pharmacology, 175:3844-3856. doi: 10.1111/bph.14454
  • Weinsanto I, Laux-Biehlmann A, Mouheiche J, Maduna T, Delalande F, Chavant V, Darbon P, Charlet A, Poisbeau P, Lamshöft M, Van Dorsselaer A, Cianferani S, Parat M-O, Goumon Y. Lithium reverses mechanical allodynia through a mu opioid-dependent mechanism (2018). Molecular Pain, 14:1744806917754142. doi: 10.1177/1744806917754142

Reviews

  • Maduna T, Lelievre V. (2016). Neuropeptides shaping the central nervous system development: Spatiotemporal actions of VIP and PACAP through complementary signaling pathways. Journal of Neuroscience Research. 94:1472-1487. doi: 10.1002/jnr.23915

Book Chapters

  • Maduna T, Loos, B (2021). Alzheimer’s Disease – Molecular Defect, Public Perceptions and Stigma in South Africa. Health Communication and Disease in Africa: Beliefs, Traditions and Stigma, Springer Singapore, pages 63-99, ISBN 978-981-16-2546-6. doi: 10.1007/978-981-16-2546-6_4
  • Maduna T, duToit A, Loos B (2021). Chapter 18 – Macroautophagy and chaperone-mediated autophagy in aging. Factors Affecting Neurological Aging, Academic Press, pages 199-211, ISBN 9780128179901. doi: 10.1016/B978-0-12-817990-1.00018-4