Dr. med. Maximilian Lenz

RNA-based regulation and epigenetic modifications

Institute for Anatomy and Cell Biology

Department of Neuroanatomy

Albertstraße 23
D - 79104 Freiburg
Germany

+49 761 203 8424

 maximilian.lenz@anat.uni-freiburg.de

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Vita

Since 2017Postdoctoral fellow and Group Leader at Institute for Anatomy and Cell Biology, Department of Neuroanatomy, Albert-Ludwigs-University; Freiburg
2016 - 2017Postdoctoral fellow at Institute of Anatomy II, Heinrich-Heine-University; Düsseldorf
2017Doctoral Thesis (M.D.) „Einfluss repetitiver Magnetstimulation auf exzitatorische und inhibitorische Synapsen von Prinzipalneuronen in organotypischen entorhino-hippokampalen Schnittkulturen der Maus“ (summa cum laude)
2015Licensed as Physician in Germany
2014Visiting Researcher at Chaim Sheba Medical Center; Tel HaShomer, Israel (Nicola Maggio MD/PhD)
2008 - 2015Medical School at Johann Wolfgang Goethe-University; Frankfurt/Main

Awards

2017Thesis award of the Dr. Walter and Luise Freundlich Stiftung
2016‚Nachwuchspreis‘ of Anatomical Society
2016FENS-IBRO/PERC Travel Grant (FENS Forum 2016, Copenhagen)
2015Poster award at 1<sup>st</sup> International Brain Stimulation Conference, Singapur
2014Young Investigator Award of Anatomical Society

Other Qualifications

2021Professional Qualification “Fachanatom Anatomische Gesellschaft”
2020Baden-Württemberg Certificate for Teaching and Learning at University Level
2017Review Editor „Frontiers in Molecular Neuroscience“
2012Licensed for Animal Handling (according to FELASA-Cat. B)
2010 - 2015Fellow of German Academic Scholarship Foundation

Selected Publications

  • Lenz M, Kruse P, Eichler A, Straehle J, Beck J, Deller T, Vlachos A. (2021) All-trans retinoic acid induces synaptic plasticity in human cortical neurons. Elife. 10:e63026.
  • Lenz M, Eichler A, Kruse P, Strehl A, Rodriguez-Rozada S, Goren I, Yogev N, Frank S, Waisman A, Deller T, Jung S, Maggio N, Vlachos A. (2020) Interleukin 10 Restores Lipopolysaccharide-Induced Alterations in Synaptic Plasticity Probed by Repetitive Magnetic Stimulation. Front Immunol. 11:614509.
  • Masuda T, Amann L, Straszewski O, Lenz M, Errico P, Snaidero N, Costa Jordao MJ, Böttcher C, Kierdorf K, Jung S, Priller J, Misgeld T, Vlachos A, Meyer-Luehmann M, Knobeloch KP, Prinz M. (2020) Novel HexB-based tools for studying microglia in the CNS. Nat Immunol. 21:802-815.
  • Lenz M, Shimon MB, Benninger F, Neufeld MY, Shavit-Stein E, Vlachos A, Maggio N. (2019) Systemic thrombin inhibition ameliorates seizures in a mouse model of pilocarpine-induced status epilepticus. J Mol Med (Berl). 97:1567-1574.
  • Lenz M, Galanis C, Müller-Dahlhaus F, Opitz A, Wierenga CJ, Ziemann U, Deller T, Funke K, Vlachos A. (2016) Repetitive magnetic stimulation induces plasticity of inhibitory synapses. Nat Commun. 7:10020.

Reviews

  • Lenz M, Eichler A, Vlachos A. (2021) Monitoring and Modulating Inflammation-Associated Alterations in Synaptic Plasticity: Role of Brain Stimulation and the Blood-Brain Interface. Biomolecules.  11:359.
  • Lenz M, Vlachos A. (2016) Releasing the Cortical Brake by Non-Invasive Electromagnetic Stimulation? rTMS Induces LTD of GABAergic Neurotransmission. Front Neural Circuits. 10:96. eCollection 2016.

Book Chapters

  • Lenz M, Müller-Dahlhaus F, Vlachos A. Cellular and Molecular Mechanisms of rTMS-induced Neural Plasticity. Therapeutic rTMS in Neurology: Principles, Evidence, and Practice Recommendations, Springer International Publishing Switzerland, S.11-22, 2016.